Human African trypanosomiasis (HAT), or sleeping sickness, is a parasitic infection that
is almost invariably fatal unless treated. It is a neglected tropical disease that occurs in
sub-Saharan Africa.
The infection is transmitted to humans through the bite of an infected tsetse fly. The
parasite multipl...
Ergan, B;
Oczkowski, S;
Rochwerg, B;
Carlucci, A;
Chatwin, M;
Clini, E;
Elliott, M;
Gonzalez-Bermejo, J;
Hart, N;
Lujan, M;
Nasilowski, J;
Nava, S;
Pepin, J. L;
Pisani, L;
Storre, J. H;
Wijkstra, P;
Tonia, T;
Boyd, J;
Scala, R;
Windisch, W.
While the role of acute non-invasive ventilation (NIV) has been shown to improve outcome in acute life-threatening hypercapnic respiratory failure in COPD, the evidence of clinical efficacy of long-term home NIV (LTH-NIV) for management of COPD is less. This document provides evidence-based recommendatio...
Holguin, Fernando;
Cardet, Juan Carlos;
Chung, Kian Fan;
Diver, Sarah;
Ferreira, Diogenes S;
Fitzpatrick, Anne;
Gaga, Mina;
Kellermeye, Liz;
Khurana, Sandhya;
Knight, Shandra;
McDonald, Vanessa M;
Morgan, Rebecca L;
Ortega, Victor E;
Rigau, David;
Subbarao, Padmaja;
Tonia, Thomy;
Adcock, Ian M;
Bleecker, Eugene R;
Brightling, Chris;
Boulet, Louis-Philippe;
Cabana, Michael;
Castro, Mario;
Hamerlijnck, Dominique;
Jarjour, Nizar;
Konno, Satoshi;
Shen, Huahao;
Vitary, Cathy;
Bush, Andy.
This document provides clinical recommendations for the management of severe asthma. Comprehensive evidence syntheses, including meta-analyses, were performed to summarise all available evidence relevant to the Task Force's questions. The evidence was appraised using the Grading of Recommendations, Asses...
Duijts, Liesbeth;
van Meel, Evelien R;
Moschino, Laura;
Baraldi, Eugenio;
Barnhoorn, Magda;
Bramer, Wichor M;
Bolton, Charlotte E;
Boyd, Jeanette;
Buchvald, Frederik;
del Cerro, Maria Jesus;
Colin, Andrew A;
Ersu, Refika;
Greenough, Anne;
Halvorsen, Thomas;
Gremmen, Christiaan;
Kamphuis, Juliette;
Kotecha, Sailesh;
Rooney-Otero, Kathleen;
Schulzke, Sven;
Wilson, Andrew;
Rigau, David;
Morgan, Rebecca L;
Tonia, Thomy;
Roehr, Charles C;
Pijnenburg, Marielle W.
This document provides recommendations for monitoring and treatment of children in whom bronchopulmonary dysplasia (BPD) has been established and were discharged from the hospital, or who were older than 36 weeks of postmenstrual age. The guideline was based on pre-defined Population, Intervention, Com...
This guideline covers identifying and treating primary hypertension (high blood pressure) in people aged 18 and over, including people with type 2 diabetes. It aims to reduce the risk of cardiovascular problems such as heart attacks and strokes by helping healthcare professionals to diagnose hypertension...
To develop an evidence-based clinical practice guideline for the prevention of oral mucositis in children (0-18 years) receiving treatment for cancer or undergoing haematopoietic stem cell transplantation (HSCT).
The Mucositis Prevention Guideline Development Group was interdisciplinary and included in...
This guideline covers the care of women at increased risk of, or with symptoms and signs of, preterm labour (before 37 weeks), and women having a planned preterm birth. It aims to reduce the risks of preterm birth for the baby and describes treatments to prevent or delay early labour and birth....
Generar recomendaciones basadas en la mejor evidencia disponible acerca del manejo clínico de las
personas de 15 años y más con Ataque Cerebrovascular isquémico....
This guideline covers interventions in secondary and further education to prevent and reduce
alcohol use among children and young people aged 11 up to and including 18. It also covers people
aged 11 to 25 with special educational needs or disabilities in full-time education. It will also be
relevant to c...
Panaccione, R;
Steinhart, A. H;
Bressler, B;
Khanna, R;
Marshall, J. K;
Targownik, L;
Bitton, A;
Borgaonkr, M;
Chauhan, U;
Halloran, B;
Jones, J;
Kennedy, E;
Leontiadis, G. I;
Jr Loftus, E. V;
Meddings, J;
Moayyedi, P;
Plamondon, S.
Crohn's disease (CD) is a lifelong illness with substantial morbidity, although new therapies and treatment paradigms have been developed. We provide guidance for treatment of ambulatory patients with mild to severe active luminal CD. We performed a systematic review to identify published studies of the ...
