Fraenkel, Liana;
Bathon, Joan;
England, Bryant;
St Clair, William;
Arayssi, Thurayya;
Carandang, Kristine;
Deane, Kevin;
Genovese, Mark;
Huston, Kent;
Kerr, Gail;
Akl, Elie;
Turner, Amy.
To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluat...
The incidence and prevalence of Crohn's disease (CD) is rising globally. Patients with moderate to severe CD are at high risk for needing surgery and hospitalization and for developing disease-related complications, corticosteroid dependence, and serious infections. Optimal management of outpatients with...
To describe evidence-based practice for managing the labour, delivery, and postpartum care of people with physical disabilities in Canada. This guideline addresses the needs of people with physical disabilities, with a focus on conditions that affect strength and mobility, as well as those that affect ne...
To provide an evidence-based algorithm to guide the diagnosis and management of pregnancy of unknown location and tubal and nontubal ectopic pregnancy. All patients of reproductive age. The implementation of this guideline aims to benefit patients with positive β-human chorionic gonadotropin results and...
To provide an update on current recommendations for cytomegalovirus (CMV) infection during pregnancy. The objectives of this guideline are: To improve perinatal care providers’ awareness of the consequences of maternal CMV infection for the fetus and the infant; To emphasize the importance of educating...
Paterson, Ian;
White, James;
Butler, Craig;
Connelly, Kim;
Guerra, Peter;
Hill, Michael;
Sarak, Bradley;
Sterns, Laurence;
Verma, Atul;
Wan, Douglas;
Crean, Andrew;
Grosse-Wortmann, Lars;
Hanneman, Kate;
Leipsic, Jonathon;
Manlucu, Jaimie;
Villemaire, Christine;
Wald, Rachel;
Windram, Jonathan.
Magnetic resonance imaging (MRI) is often considered the gold-standard test for characterizing cardiac as well as noncardiac structure and function. However, many patients with cardiac implantable electronic devices (CIEDs) and/or severe renal dysfunction are unable to undergo this test because of safety...
Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American Coll...
Pottercher, Julien;
Lefort, Hugues;
Adam, Philippe;
Barbier, Oliver;
Bouzat, Pierre;
Charbit, Jonathan;
Galinski, Michel;
Garringue, Delphine;
Gauss, Tobias;
Georg, Yannick.
To provide healthcare professionals with comprehensive multidisciplinary expert recommendations for the acute care of severe limb trauma patients, both during the prehospital phase and after admission to a Trauma Centre. A consensus committee of 21 experts was formed. A formal conflict-of-interest (COI) ...
Ansai, Shin-Ichi;
Umeayashi, Yoshihiro;
Katsumata, Noriyuki;
Kato, Hiroshi;
Kadono, Takafumi;
Takai, Toshihiro;
Namiki, Takeshi;
Nakagawa, Masahiro;
Soejima, Toshinori;
Koga, Hiroshi;
Sugaya, Makoto.
In consideration of the development of treatment options for squamous cell carcinoma (SCC), the Japanese Skin Cancer Society issued the first guidelines of SCC in 2007 and revised them in 2015. Here, we report the English version of the 2020 edition of the Japanese SCC guidelines. The first half of this ...
Clinical question What are the benefits and harms of sodium-glucose cotransporter 2 (SGLT-2) inhibitors and glucagon-like peptide 1 (GLP-1) receptor agonists when added to usual care (lifestyle interventions and/or other diabetes drugs) in adults with type 2 diabetes at different risk for cardiovascular ...